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Treating cancer when pRb and p53 cannot be reactivated

Activation of oncoproteins and inactivation of tumor suppressors induces tumorigenesis. When these events happen upstream of pRb and p53, cancer therapies may initially succeed and then fail when pRb and p53 are activated and then re-inactivated. Therapies might succeed if they remain effective when...

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Foilsithe in:Mol Cell Oncol
Príomhúdar: Zhu, Liang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905341/
https://ncbi.nlm.nih.gov/pubmed/27308498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1004954
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