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The Membrane Proximal External Region of the HIV-1 Envelope Glycoprotein gp41 Contributes to the Stabilization of the Six-Helix Bundle Formed with a Matching N′ Peptide

The HIV-1 envelope glycoprotein gp41 undergoes a sequence of extensive conformational changes while participating in the fusion of the virus with the host cell. Since the discovery of its postfusion conformation, the structure and function of the protease-resistant six-helix bundle (6-HB) have been...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Noah, Eran, Biron, Zohar, Naider, Fred, Arshava, Boris, Anglister, Jacob
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459237/
https://ncbi.nlm.nih.gov/pubmed/18540633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7023139
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