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The C4 region as a target for HIV entry inhibitors – NMR Mapping of the interacting segments of T20 and gp120
The peptide T20, which corresponds to a sequence in the C-terminal segment of the HIV-1 trans-membrane glycoprotein gp41, is a strong entry inhibitor of HIV-1. It has been assumed that T20 inhibits HIV-1 infection by binding to the trimer formed by the N-terminal helical region (HR1) of gp41, preven...
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| Publicado no: | FEBS J |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4715528/ https://ncbi.nlm.nih.gov/pubmed/26432362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13541 |
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