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An Optimally constrained V3 peptide is a better immunogen than its linear homolog or HIV-1 gp120
Synthetic peptides offer an attractive option for development of a V3-directed vaccine. However, immunization with flexible linear peptides may result in an immune response to multiple conformations, many of which differ from the native conformation of the corresponding region in the protein. Here w...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862131/ https://ncbi.nlm.nih.gov/pubmed/20347111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.03.007 |
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