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An extended CCR5-ECL2 peptide forms a helix that binds HIV-1 gp120 through non-specific hydrophobic interactions

The chemokine receptor CCR5 serves as a co-receptor for the Human Immunodefficiency Virus type-1, HIV-1. The CCR5 N-terminal segment, the second extracellular loop (ECL2) and the transmembrane helices have been implicated in binding the envelope glycoprotein gp120. Peptides corresponding to the sequ...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:FEBS J
Asıl Yazarlar: Abayev, Meital, Moseri, Adi, Tchaicheeyan, Oren, Kessler, Naama, Arshava, Boris, Naider, Fred, Scherf, Tali, Anglister, Jacob
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439283/
https://ncbi.nlm.nih.gov/pubmed/25703038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13243
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