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Evidence That the Transition of HIV-1 Gp41 into a Six-Helix Bundle, Not the Bundle Configuration, Induces Membrane Fusion

Many viral fusion proteins exhibit a six-helix bundle as a core structure. HIV Env–induced fusion was studied to resolve whether membrane merger was due to the transition into the bundle configuration or occurred after bundle formation. Suboptimal temperature was used to arrest fusion at an intermed...

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Bibliografiske detaljer
Main Authors: Melikyan, Grigory B., Markosyan, Ruben M., Hemmati, Hila, Delmedico, Mary K., Lambert, Dennis M., Cohen, Fredric S.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192659/
https://ncbi.nlm.nih.gov/pubmed/11038187
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