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The Six-Helix Bundle of Human Immunodeficiency Virus Env Controls Pore Formation and Enlargement and Is Initiated at Residues Proximal to the Hairpin Turn

Residues that create the grooves of the human immunodeficiency virus type 1 (HIV-1) Env triple-stranded coiled coil (HR1) and the residues that pack into the grooves (HR2) to complete the formation of the six-helix bundle (6HB) were mutated. The extent and kinetics of fusion as well as pore enlargem...

詳細記述

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書誌詳細
主要な著者: Markosyan, Ruben M., Leung, Michael Y., Cohen, Fredric S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748045/
https://ncbi.nlm.nih.gov/pubmed/19625396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00316-09
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