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Development of a Humanized C1q A Chain Knock-in Mouse: Assessment of Antibody Independent β-Amyloid Induced Complement Activation

Evidence has been accumulating for a role for inflammation in the development of Alzheimer’s disease (AD), a progressive neurodegenerative disorder causing a common form of dementia in the elderly. C1q, part of the initiation component of the classical complement pathway (CCP), is associated with β-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Ming, Ager, Rahasson R., Fraser, Deborah A., Tjokro, Natalia O., Tenner, Andrea J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453780/
https://ncbi.nlm.nih.gov/pubmed/18400300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.02.022
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