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Antibodies in a heavy chain knock-in mouse exhibit characteristics of early heavy chain rearrangement

Studies in autoantibody transgenic mice have demonstrated receptor editing rearrangements at antibody heavy and light chain loci. However, the physiologic role of heavy chain editing (V(H) replacement and rearrangement on the second allele) has been called into question. It is unclear if additional...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yunk, Lenka, Meng, Wenzhao, Cohen, Philip L., Eisenberg, Robert A., Luning Prak, Eline T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700953/
https://ncbi.nlm.nih.gov/pubmed/19542457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804060
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