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Antibodies in a heavy chain knock-in mouse exhibit characteristics of early heavy chain rearrangement
Studies in autoantibody transgenic mice have demonstrated receptor editing rearrangements at antibody heavy and light chain loci. However, the physiologic role of heavy chain editing (V(H) replacement and rearrangement on the second allele) has been called into question. It is unclear if additional...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700953/ https://ncbi.nlm.nih.gov/pubmed/19542457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804060 |
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