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Selection of individual V(H) genes occurs at the pro-B to pre-B cell transition

B cells are subjected to selection at multiple checkpoints during their development. The selection of antibody heavy chains is difficult to study because of the large diversity of the CDR3. In order to study the selection of individual antibody heavy chain variable region genes (V(H)), we performed...

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Detalhes bibliográficos
Main Authors: Meng, Wenzhao, Yunk, Lenka, Wang, Li-San, Maganty, Avinash, Xue, Emily, Cohen, Philip L., Eisenberg, Robert A., Weigert, Martin G., Mancini, Stephane J.C., Luning Prak, Eline T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150439/
https://ncbi.nlm.nih.gov/pubmed/21746964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100207
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