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Alternative mechanisms of receptor editing in autoreactive B cells
Pathogenic anti-DNA antibodies expressed in systemic lupus erythematosis bind DNA mainly through electrostatic interactions between the positively charged Arg residues of the antibody complementarity determining region (CDR) and the negatively charged phosphate groups of DNA. The importance of Arg i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084116/ https://ncbi.nlm.nih.gov/pubmed/21471456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019389108 |
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