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Development of a Humanized C1q A Chain Knock-in Mouse: Assessment of Antibody Independent β-Amyloid Induced Complement Activation
Evidence has been accumulating for a role for inflammation in the development of Alzheimer’s disease (AD), a progressive neurodegenerative disorder causing a common form of dementia in the elderly. C1q, part of the initiation component of the classical complement pathway (CCP), is associated with β-...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2453780/ https://ncbi.nlm.nih.gov/pubmed/18400300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.02.022 |
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