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Retroviral Integration Process in the Human Genome: Is It Really Non-Random? A New Statistical Approach
Retroviral vectors are widely used in gene therapy to introduce therapeutic genes into patients' cells, since, once delivered to the nucleus, the genes of interest are stably inserted (integrated) into the target cell genome. There is now compelling evidence that integration of retroviral vecto...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2453317/ https://ncbi.nlm.nih.gov/pubmed/18688267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000144 |
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