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Transcription Factor Binding Sites Are Genetic Determinants of Retroviral Integration in the Human Genome
Gamma-retroviruses and lentiviruses integrate non-randomly in mammalian genomes, with specific preferences for active chromatin, promoters and regulatory regions. Gene transfer vectors derived from gamma-retroviruses target at high frequency genes involved in the control of growth, development and d...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2642719/ https://ncbi.nlm.nih.gov/pubmed/19238208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004571 |
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