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Retroviral Integration Process in the Human Genome: Is It Really Non-Random? A New Statistical Approach

Retroviral vectors are widely used in gene therapy to introduce therapeutic genes into patients' cells, since, once delivered to the nucleus, the genes of interest are stably inserted (integrated) into the target cell genome. There is now compelling evidence that integration of retroviral vecto...

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Detaylı Bibliyografya
Asıl Yazarlar: Ambrosi, Alessandro, Cattoglio, Claudia, Di Serio, Clelia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453317/
https://ncbi.nlm.nih.gov/pubmed/18688267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000144
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