ALTERED DYNAMICS OF Kv1.3 CHANNEL COMPARTMENTALIZATION IN THE IMMUNOLOGICAL SYNAPSE IN SYSTEMIC LUPUS ERYTHEMATOSUS,

Aberrant T cell responses during T cell activation and immunological synapse (IS) formation have been described in systemic lupus erythematosus (SLE). Kv1.3 potassium channels are expressed in T cells where they compartmentalize at the IS and play a key role in T cell activation by modulating Ca(2+)...

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Autors principals: Nicolaou, Stella A., Szigligeti, Peter, Neumeier, Lisa, Lee, Susan Molleran, Duncan, Heather J., Kant, Shashi K., Mongey, Anne Barbara, Filipovich, Alexandra H., Conforti, Laura
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453311/
https://ncbi.nlm.nih.gov/pubmed/17579055
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