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The relationship between dNTP pool levels and mutagenesis in an Escherichia coli NDP kinase mutant
Loss of nucleoside diphosphate kinase (Ndk) function in Escherichia coli results in an increased frequency of spontaneous mutation and an imbalance in dNTP pool levels. It is presumed that the imbalance in dNTP pool levels is responsible for the mutator phenotype of an E. coli ndk mutant. A human ho...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2453072/ https://ncbi.nlm.nih.gov/pubmed/18621712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802816105 |
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