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Escherichia coliNucleoside Diphosphate Kinase Mutants Depend on Translesion DNA Synthesis To Prevent Mutagenesis

Escherichia colinucleoside diphosphate (NDP) kinase mutants have an increased frequency of spontaneous mutation, possibly due to uracil misincorporation into DNA. Here we show that NDP kinase mutants are dependent on translesion DNA synthesis, often a mutagenic form of DNA synthesis, to prevent muta...

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Detalhes bibliográficos
Main Authors: Nordman, Jared, Wright, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165513/
https://ncbi.nlm.nih.gov/pubmed/21725024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05393-11
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