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Mutational consequences of dNTP pool imbalances in E. coli
The accuracy of DNA synthesis depends on the accuracy of the polymerase as well as the quality and concentration(s) of the available 5′-deoxynucleoside-triphosphate DNA precursors (dNTPs). The relationships between dNTPs and error rates have been studied in vitro, but only limited insights exist int...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534869/ https://ncbi.nlm.nih.gov/pubmed/23218950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.10.011 |
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