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Effect of dNTP pool alterations on fidelity of leading and lagging strand DNA replication in E. coli

The fidelity with which organisms replicate their chromosomal DNA is of considerable interest. Detailed studies in the bacterium Escherichia coli have indicated that the fidelity of leading- and lagging-strand DNA replication is not the same, based on experiments in which the orientation of certain...

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Autors principals: Gawel, Damian, Fijalkowska, Iwona J., Jonczyk, Piotr, Schaaper, Roel M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947270/
https://ncbi.nlm.nih.gov/pubmed/24269257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2013.11.003
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