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Replication fidelity in E. coli: differential leading and lagging strand effects for dnaE antimutator alleles
DNA Pol III holoenzyme (HE) is the major DNA replicase of Escherichia coli. It is a highly accurate enzyme responsible for simultaneously replicating the leading- and lagging DNA strands. Interestingly, the fidelity of replication for the two DNA strands is unequal, with a higher accuracy for laggin...
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| Veröffentlicht in: | DNA Repair (Amst) |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6801068/ https://ncbi.nlm.nih.gov/pubmed/31324532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102643 |
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