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High-accuracy lagging-strand DNA replication mediated by DNA polymerase dissociation

The fidelity of DNA replication is a critical factor in the rate at which cells incur mutations. Due to the antiparallel orientation of the two chromosomal DNA strands, one strand (leading strand) is replicated in a mostly processive manner, while the other (lagging strand) is synthesized in short s...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Maslowska, Katarzyna H., Makiela-Dzbenska, Karolina, Mo, Jin-Yao, Fijalkowska, Iwona J., Schaaper, Roel M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910852/
https://ncbi.nlm.nih.gov/pubmed/29610333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720353115
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