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Role of Escherichia coli DNA Polymerase I in chromosomal DNA replication fidelity

We have investigated the possible role of E. coli DNA polymerase I in chromosomal replication fidelity. This was done by substituting the chromosomal polA gene by the polAexo variant containing an inactivated 3'→5' exonuclease, which serves as a proofreader for this enzyme's misinsert...

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Detalhes bibliográficos
Main Authors: Makiela-Dzbenska, Karolina, Jaszczur, Malgorzata, Banach-Orlowska, Magdalena, Jonczyk, Piotr, Schaaper, Roel M., Fijalkowska, Iwona J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818720/
https://ncbi.nlm.nih.gov/pubmed/19843230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06921.x
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