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Replication fidelity in E. coli: differential leading and lagging strand effects for dnaE antimutator alleles

DNA Pol III holoenzyme (HE) is the major DNA replicase of Escherichia coli. It is a highly accurate enzyme responsible for simultaneously replicating the leading- and lagging DNA strands. Interestingly, the fidelity of replication for the two DNA strands is unequal, with a higher accuracy for laggin...

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Vydáno v:DNA Repair (Amst)
Hlavní autoři: Makiela-Dzbenska, Karolina, Maslowska, Katarzyna H., Kuban, Wojciech, Gawel, Damian, Jonczyk, Piotr, Schaaper, Roel M., Fijalkowska, Iwona J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801068/
https://ncbi.nlm.nih.gov/pubmed/31324532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102643
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