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Mutational consequences of dNTP pool imbalances in E. coli

The accuracy of DNA synthesis depends on the accuracy of the polymerase as well as the quality and concentration(s) of the available 5′-deoxynucleoside-triphosphate DNA precursors (dNTPs). The relationships between dNTPs and error rates have been studied in vitro, but only limited insights exist int...

詳細記述

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書誌詳細
主要な著者: Schaaper, Roel M., Mathews, Christopher K.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534869/
https://ncbi.nlm.nih.gov/pubmed/23218950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.10.011
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