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Allosteric Motions in Structures of Yeast NAD(+)-specific Isocitrate Dehydrogenase
Mitochondrial NAD(+)-specific isocitrate dehydrogenases (IDHs) are key regulators of flux through biosynthetic and oxidative pathways in response to cellular energy levels. Here we present the first structures of a eukaryotic member of this enzyme family, the allosteric, hetero-octameric, NAD(+)-spe...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447628/ https://ncbi.nlm.nih.gov/pubmed/18256028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708719200 |
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