Intersubunit Disulfide Isomerization Controls Membrane Fusion of Human T-Cell Leukemia Virus Env

Human T-cell leukemia virus (HTLV-1) Env carries a typical disulfide isomerization motif, C(225)XXC, in the C-terminal domain SU. Here we have tested whether this motif is used for isomerization of the intersubunit disulfide of Env and whether this rearrangement is required for membrane fusion. We i...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Kejun, Zhang, Shujing, Kronqvist, Malin, Wallin, Michael, Ekström, Maria, Derse, David, Garoff, Henrik
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2008
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446982/
https://ncbi.nlm.nih.gov/pubmed/18480461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00448-08
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