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Intersubunit Disulfide Isomerization Controls Membrane Fusion of Human T-Cell Leukemia Virus Env

Human T-cell leukemia virus (HTLV-1) Env carries a typical disulfide isomerization motif, C(225)XXC, in the C-terminal domain SU. Here we have tested whether this motif is used for isomerization of the intersubunit disulfide of Env and whether this rearrangement is required for membrane fusion. We i...

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書誌詳細
主要な著者: Li, Kejun, Zhang, Shujing, Kronqvist, Malin, Wallin, Michael, Ekström, Maria, Derse, David, Garoff, Henrik
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446982/
https://ncbi.nlm.nih.gov/pubmed/18480461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00448-08
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