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Isomerization of the intersubunit disulphide-bond in Env controls retrovirus fusion
The membrane fusion activity of murine leukaemia virus Env is carried by the transmembrane (TM) and controlled by the peripheral (SU) subunit. We show here that all Env subunits of the virus form disulphide-linked SU–TM complexes that can be disrupted by treatment with NP-40, heat or urea, or by Ca(...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1271652/ https://ncbi.nlm.nih.gov/pubmed/14685283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600012 |
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