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Kinetic Analyses of the Surface-Transmembrane Disulfide Bond Isomerization-Controlled Fusion Activation Pathway in Moloney Murine Leukemia Virus

The surface (SU) and transmembrane (TM) subunits of Moloney murine leukemia virus (Mo-MLV) Env are disulfide linked. The linking cysteine in SU is part of a conserved CXXC motif in which the other cysteine carries a free thiol. Recently, we showed that receptor binding activates its free thiol to is...

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Hlavní autoři: Wallin, Michael, Löving, Robin, Ekström, Maria, Li, Kejun, Garoff, Henrik
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280236/
https://ncbi.nlm.nih.gov/pubmed/16254321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.13856-13864.2005
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