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Intersubunit Disulfide Isomerization Controls Membrane Fusion of Human T-Cell Leukemia Virus Env

Human T-cell leukemia virus (HTLV-1) Env carries a typical disulfide isomerization motif, C(225)XXC, in the C-terminal domain SU. Here we have tested whether this motif is used for isomerization of the intersubunit disulfide of Env and whether this rearrangement is required for membrane fusion. We i...

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Bibliografske podrobnosti
Main Authors: Li, Kejun, Zhang, Shujing, Kronqvist, Malin, Wallin, Michael, Ekström, Maria, Derse, David, Garoff, Henrik
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446982/
https://ncbi.nlm.nih.gov/pubmed/18480461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00448-08
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