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Intersubunit Disulfide Isomerization Controls Membrane Fusion of Human T-Cell Leukemia Virus Env

Human T-cell leukemia virus (HTLV-1) Env carries a typical disulfide isomerization motif, C(225)XXC, in the C-terminal domain SU. Here we have tested whether this motif is used for isomerization of the intersubunit disulfide of Env and whether this rearrangement is required for membrane fusion. We i...

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Bibliografische gegevens
Hoofdauteurs: Li, Kejun, Zhang, Shujing, Kronqvist, Malin, Wallin, Michael, Ekström, Maria, Derse, David, Garoff, Henrik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446982/
https://ncbi.nlm.nih.gov/pubmed/18480461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00448-08
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