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Prevention of Drug Carryover Effects in Studies Assessing Antimycobacterial Efficacy of TMC207
The levels of TMC207 (R207910) that can be reached in mouse organs and the sputa of treated patients easily exceed the MIC of the compound and can therefore interfere with in vitro bacterial titrations. We studied the usefulness of protein-enriched media for the prevention of such drug carryover eff...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2446915/ https://ncbi.nlm.nih.gov/pubmed/18480227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00177-08 |
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