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Purification, crystallization and preliminary X-­ray diffraction studies to near-atomic resolution of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus

In recent years, dihydrodipicolinate synthase (DHDPS; EC 4.2.1.52) has received considerable attention from both mechanistic and structural viewpoints. DHDPS is part of the diaminopimelate pathway leading to lysine, coupling (S)-aspartate-β-semialdehyde with pyruvate via a Schiff base to a conserved...

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Main Authors: Burgess, Benjamin R., Dobson, Renwick C. J., Dogovski, Con, Jameson, Geoffrey B., Parker, Michael W., Perugini, Matthew A.
格式: Artigo
語言:Inglês
出版: International Union of Crystallography 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443978/
https://ncbi.nlm.nih.gov/pubmed/18607102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108016746
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