The purification, crystallization and preliminary X-­ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum

In recent years, dihydrodipicolinate synthase (DHDPS; EC 4.2.1.52) has received considerable attention from both mechanistic and structural viewpoints. This enzyme, which is part of the diaminopimelate pathway leading to lysine, couples (S)-aspartate-β-semialdehyde with pyruvate via a Schiff base to...

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Hlavní autoři: Dobson, Renwick C. J., Atkinson, Sarah C., Gorman, Michael A., Newman, Janet M., Parker, Michael W., Perugini, Matthew A.
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2008
Témata:
Crystallization Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374160/
https://ncbi.nlm.nih.gov/pubmed/18323610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108002819
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