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Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the psychrophile Shewanella benthica

Dihydrodipicolinate synthase (DHDPS) is an oligomeric enzyme that catalyzes the first committed step of the lysine-biosynthesis pathway in plants and bacteria, which yields essential building blocks for cell-wall and protein synthesis. DHDPS is therefore of interest to drug-discovery research as wel...

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Detalhes bibliográficos
Main Authors: Wubben, Jacinta M., Dogovski, Con, Dobson, Renwick C. J., Codd, Rachel, Gerrard, Juliet A., Parker, Michael W., Perugini, Matthew A.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001662/
https://ncbi.nlm.nih.gov/pubmed/21045309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110036791
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