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A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine
BACKGROUND: p53 is an important tumour suppressor with a known role in the later stages of colorectal cancer, but its relevance to the early stages of neoplastic initiation remains somewhat unclear. Although p53-dependent regulation of Wnt signalling activity is known to occur, the importance of the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443808/ https://ncbi.nlm.nih.gov/pubmed/18533991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-162 |
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