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Prion Protein Complexed to N2a Cellular RNAs through Its N-terminal Domain Forms Aggregates and Is Toxic to Murine Neuroblastoma Cells

Conversion of the cellular prion protein (PrP(C)) into its altered conformation, PrP(Sc), is believed to be the major cause of prion diseases. Although PrP is the only identified agent for these diseases, there is increasing evidence that other molecules can modulate the conversion. We have found th...

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Bibliografske podrobnosti
Main Authors: Gomes, Mariana P. B., Millen, Thiago A., Ferreira, Priscila S., e Silva, Narcisa L. Cunha, Vieira, Tuane C. R. G., Almeida, Marcius S., Silva, Jerson L., Cordeiro, Yraima
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443653/
https://ncbi.nlm.nih.gov/pubmed/18456654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802102200
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