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The “Jekyll and Hyde” Actions of Nucleic Acids on the Prion-like Aggregation of Proteins

Protein misfolding results in devastating degenerative diseases and cancer. Among the culprits involved in these illnesses are prions and prion-like proteins, which can propagate by converting normal proteins to the wrong conformation. For spongiform encephalopathies, a real prion can be transmitted...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Silva, Jerson L., Cordeiro, Yraima
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957035/
https://ncbi.nlm.nih.gov/pubmed/27288413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R116.733428
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