TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice

Transforming growth factor β–activated kinase 1 (TAK1), a member of the MAPKKK family, is a key mediator of proinflammatory and stress signals. Activation of TAK1 by proinflammatory cytokines and T and B cell receptors induces the nuclear localization of nuclear factor κB (NF-κB) and the activation...

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Main Authors: Tang, Minghui, Wei, Xudong, Guo, Yinshi, Breslin, Peter, Zhang, Shubin, Zhang, Shanshan, Wei, Wei, Xia, Zhenbiao, Diaz, Manuel, Akira, Shizuo, Zhang, Jiwang
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442639/
https://ncbi.nlm.nih.gov/pubmed/18573910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080297
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