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Molecular and cellular mechanisms of aging in hematopoietic stem cells and their niches

Aging drives the genetic and epigenetic changes that result in a decline in hematopoietic stem cell (HSC) functioning. Such changes lead to aging-related hematopoietic/immune impairments and hematopoietic disorders. Understanding how such changes are initiated and how they progress will help in the...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Zhang, Lei, Mack, Ryan, Breslin, Peter, Zhang, Jiwang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686726/
https://ncbi.nlm.nih.gov/pubmed/33228751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00994-z
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