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Survival and maintenance of regulatory T cells require the kinase TAK1

Regulatory T (Treg) cells play a central role in regulating peripheral immune tolerance and preventing autoimmunity. Despite the extensive studies on the development of Treg cells, the molecular mechanisms that maintain the population of committed Treg cells remain poorly understood. We show here th...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Chang, Jae-Hoon, Hu, Hongbo, Sun, Shao-Cong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579655/
https://ncbi.nlm.nih.gov/pubmed/25891214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.27
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