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TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice
Transforming growth factor β–activated kinase 1 (TAK1), a member of the MAPKKK family, is a key mediator of proinflammatory and stress signals. Activation of TAK1 by proinflammatory cytokines and T and B cell receptors induces the nuclear localization of nuclear factor κB (NF-κB) and the activation...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442639/ https://ncbi.nlm.nih.gov/pubmed/18573910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080297 |
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