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GCUNC45 Is the First Hsp90 Co-chaperone to Show α/β Isoform Specificity

Hsp90 is an essential molecular chaperone required for the normal functioning of many key regulatory proteins in eukaryotic cells. Vertebrates have two closely related isoforms of cytosolic Hsp90 (Hsp90α and Hsp90β). However, specific functions for each isoform are largely unknown, and no Hsp90 co-c...

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Autors principals: Chadli, Ahmed, Felts, Sara J., Toft, David O.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442279/
https://ncbi.nlm.nih.gov/pubmed/18285346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C800017200
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