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Selective Inhibition of the Hsp90α isoform
The 90 kDa heat shock protein (Hsp90) is a molecular chaperone that processes nascent polypeptides into their biologically active conformations. Many of these proteins contribute to the progression of cancer, and consequently, inhibition of the Hsp90 protein folding machinery represents an innovativ...
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| Publicat a: | Angew Chem Int Ed Engl |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8086817/ https://ncbi.nlm.nih.gov/pubmed/33621416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202015422 |
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