Selective Inhibition of the Hsp90α isoform

The 90 kDa heat shock protein (Hsp90) is a molecular chaperone that processes nascent polypeptides into their biologically active conformations. Many of these proteins contribute to the progression of cancer, and consequently, inhibition of the Hsp90 protein folding machinery represents an innovativ...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Angew Chem Int Ed Engl
Prif Awduron: Mishra, Sanket J., Khandelwal, Anuj, Banerjee, Monimoy, Balch, Maurie, Peng, Shuxia, Davis, Rachel E., Merfeld, Taylor, Munthali, Vitumbiko, Deng, Junpeng, Matts, Robert, Blagg, Brian S. J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086817/
https://ncbi.nlm.nih.gov/pubmed/33621416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202015422
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