Specific mutations in a viral RNA pseudoknot drastically change ribosomal frameshifting efficiency

Many viruses regulate protein synthesis by −1 ribosomal frameshifting using an RNA pseudoknot. Frameshifting is vital for viral reproduction. Using the information gained from the recent high-resolution crystal structure of the beet western yellow virus pseudoknot, a systematic mutational analysis h...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kim, Yang-Gyun, Su, Li, Maas, Stefan, O’Neill, Analeah, Rich, Alexander
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24420/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10588689/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.25.14234
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