Specific mutations in a viral RNA pseudoknot drastically change ribosomal frameshifting efficiency

Many viruses regulate protein synthesis by −1 ribosomal frameshifting using an RNA pseudoknot. Frameshifting is vital for viral reproduction. Using the information gained from the recent high-resolution crystal structure of the beet western yellow virus pseudoknot, a systematic mutational analysis h...

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Detalles Bibliográficos
Autores principales: Kim, Yang-Gyun, Su, Li, Maas, Stefan, O’Neill, Analeah, Rich, Alexander
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1999
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC24420/
https://ncbi.nlm.nih.gov/pubmed/10588689
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