Specific mutations in a viral RNA pseudoknot drastically change ribosomal frameshifting efficiency
Many viruses regulate protein synthesis by −1 ribosomal frameshifting using an RNA pseudoknot. Frameshifting is vital for viral reproduction. Using the information gained from the recent high-resolution crystal structure of the beet western yellow virus pseudoknot, a systematic mutational analysis h...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1999
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24420/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10588689/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.25.14234 |
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