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Targeting a prokaryotic protein in a eukaryotic pathogen: identification of lead compounds against Cryptosporidiosis
Cryptosporidium parvum is an important human pathogen and potential bio-terrorism agent. No vaccines exist against C. parvum, the drugs currently approved to treat cryptosporidiosis are ineffective, and drug discovery is challenging because the parasite cannot be maintained continuously in cell cult...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2441818/ https://ncbi.nlm.nih.gov/pubmed/18215774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2007.12.010 |
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