Chargement en cours...
Factor Va alters the conformation of the Na(+)-binding loop of factor Xa in the prothrombinase complex
Structural and mutagenesis data have indicated that the 220-loop of thrombin is stabilized by a salt-bridge between Glu-217 and Lys-224, thereby facilitating the octahedral coordination of Na(+) with contributions from two carbonyl O atoms of Arg-221a and Lys-224. All three residues are also conserv...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2440691/ https://ncbi.nlm.nih.gov/pubmed/18457426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800319r |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|