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Perturbation of the tRNA Tertiary Core Differentially Affects Specific Steps of the Elongation Cycle
The tRNA tertiary core region is important for both tRNA stability and activity in the translation elongation cycle. Here we report the effects of mutating each of two highly conserved base pairs in the tertiary core of Phe-tRNA(Phe), 18-55 and 19-56, on rate and equilibrium constants for specific s...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2440604/ https://ncbi.nlm.nih.gov/pubmed/18448426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801560200 |
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